Sildenafil for the treatment of erectile dysfunction

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Dr. Germán Echeverry, MD

Sildenafil for the treatment of erectile dysfunction

Sildenafil is a medication primarily prescribed for the treatment of erectile dysfunction (ED). It is also used to treat pulmonary arterial hypertension (PAH), a condition characterized by high blood pressure in the arteries that supply the lungs.

Sildenafil is widely recognized under the brand name Viagra, which is the most well-known and commonly used brand. However, it is also available under other brand names depending on the country and manufacturer.

How sildenafil works

Sildenafil works by inhibiting an enzyme called phosphodiesterase type 5 (PDE5), which is responsible for the degradation of cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, sildenafil helps to increase the levels of cGMP, which relaxes and dilates the blood vessels in the penis, allowing for increased blood flow and facilitating an erection. In the case of PAH, sildenafil relaxes the blood vessels in the lungs, reducing the elevated blood pressure.

How long does it take to see results?

The time it takes for sildenafil to start working can vary, but it typically takes about 30 minutes to 1 hour. However, the onset of action can be affected by factors such as individual response, dosage, and whether the medication is taken on an empty stomach or with food. It's important to follow the specific instructions provided by your healthcare professional or the medication's packaging.

What side effects are possible?

Sildenafil, like any medication, may cause side effects. Common side effects include headache, flushing (redness or warmth in the face, neck, or chest), indigestion, stuffy or runny nose, dizziness, and visual disturbances such as changes in color vision or blurred vision. Rare but more serious side effects may include priapism (a painful and prolonged erection lasting more than four hours), sudden vision or hearing loss, and allergic reactions. If you experience any severe or persistent side effects, it is important to seek medical attention promptly.

Is sildenafil right for me?

Sildenafil is typically prescribed as an oral medication, available in tablet form. The dosage and frequency of administration will be determined by a healthcare professional based on individual factors such as the underlying condition being treated, medical history, and response to the medication. It's important to follow the prescribed dosage instructions and not exceed the recommended dose.

Please note that the information provided here is a general overview, and it's essential to consult a healthcare professional or pharmacist for personalized advice, specific brand names available in your region, and the most up-to-date information regarding the use, dosage, and potential side effects of sildenafil.